Chemical Colorimetric Method
Principle: Early blood glucose meters used the glucose oxidase colorimetric method. The test strip reacts with blood, changing color. After a set time, the blood drop is wiped off and the sample is returned to the meter to measure the chromatogram and obtain the blood glucose value.
Advantages: Faster than biochemical analyzers, requires less blood.
Glucose Oxidase Electrode Measurement Method
Principle: Blood glucose is measured by measuring the current generated by the reaction between glucose in the blood and glucose oxidase in the test strip. Most mainstream models on the market use the glucose oxidase measurement method.
Advantages: Faster than biochemical analyzers and chemical methods (within 30 seconds), requires less blood (less than 5 microliters).
Glucose Dehydrogenase Electrode Measurement Method (FAD)
Principle: Blood glucose is measured by measuring the current generated by the reaction between glucose in the blood and glucose dehydrogenase in the test strip.
Advantages: In addition to the advantages of oxidase, it is specific to glucose, unaffected by oxygen, easy to store, and can be used until the expiration date after opening.
PQQ (Glucos dehydrogenase) electrode measurement method
Principle: Blood glucose is measured by the current generated by the reaction between glucose in the blood and glucose dehydrogenase on the test strip. Main types include Roche Superior, Lisutan, and Omron 215.
Advantages: In addition to the advantages of oxidases, it overcomes the disadvantage of oxidases being difficult to preserve due to the low hydrogen content in the air. Generally, once opened, it can be used until the expiration date.
